Vitaelin Healthcenter

Ubiquinone and ubiquinol are both forms of CoQ10, and both are necessary to produce cellular energy. Ubiquinone is the oxidized form of CoQ10 that consumers are most familiar with; it has been taken as a supplement and studied for more than 30 years. Over the past three decades, CoQ10 has been recognized for its benefits to general health and wellness as well cardiovascular and neurological health.

In order to generate cellular energy, the body must convert ubiquinone into ubiquinol. Without this conversion, the body’s energy production process cannot be completed and energy levels cannot be sustained. Thus, both are critical to sustaining your body’s natural energy.

Declines in ubiquinol result in less cellular energy and diminished protection against oxidative stress, which produces free radicals and can damage the body’s cells, including proteins, lipids and DNA. Ubiquinol provides a strong first-stage defense against this cellular oxidative damage and needs to be replenished to maintain optimum health.

An increasing number of scientific reports indicate that dramatic decreases in ubiquinone levels and increased oxidative stress are associated with the aging process and with many age-related diseases such as cardiovascular disease, neurodegenerative disease, diabetes, cancer, fatigue and metabolic syndrome, as well as a number of other conditions.

As a healthy 20-year-old, you readily produce all of the CoQ10 you can use and efficiently convert it into ubiquinol. In fact, the predominant form of CoQ10 in the plasma and tissues of a healthy individual is the reduced ubiquinol form. However, age and disease impairs the body’s ability to produce and metabolize CoQ10. Some reasons for this include increased metabolic demand, disease, insufficient dietary intake, oxidative stress, or any combination of these things. Some reports say this decline becomes apparent around 40 years old, although it can begin as early as 20 in some cases. As the body’s ability to produce and reduce CoQ10 begins, supplementation with CoQ10 and/or ubiquinol becomes increasingly important to maintaining good health.

The recommended dose of WIN CoQ10 varies based on each individual’s needs and the specific condition being treated. However, those who are older or suspect they have decreased CoQ10 due to disease may want to start supplementing with 200-300 mg of WIN CoQ10 per day. Studies show that the CoQ10 plasma levels plateau at about two weeks at this dose. Then, 100 mg per day is a good maintenance dose.

Since ubiquinol is easily oxidized in the air, it has been difficult to develop a stable supply in a reduced supplement form. However, using advanced technology, scientists at Kaneka Corporation have been able to perfect a stabilization process by which ubiquinol remains in its reduced form outside of the body.

You can get ubiquinol as well as ubiquinone in small amounts from your diet; however, you would have to eat the foods in such large amounts as to make them an impractical resource for your CoQ10 supplementation needs. And because the body’s ability to convert ubiquinone to ubiquinol declines with age, food becomes a less practical source of ubiquinol for older individuals and those suffering from age-related conditions.

For those individuals who cannot efficiently convert CoQ10 to ubiquinol, WIN CoQ10 will restore healthy levels of CoQ10 in plasma and organs for more efficient energy production. This should result in more energy and stamina as well as better overall health. Additionally, because ubiquinol is an extremely powerful antioxidant, it offers a strong protective defense against oxidative stress and age-related diseases.

Ubiquinol is not a quick fix for those looking for increased energy. Unlike caffeine or sugar which boost energy levels quickly and can cause a “crash” later, ubiquinol offers sustained natural energy. Although it generally takes two to three weeks to restore optimal CoQ10 levels in blood plasma and tissues, most people will begin feeling the effects as their individual plasma levels start to increase, generally around the fifth day. Clinical studies are currently underway to determine if those affected by specific diseases may notice a decrease in the severity of their symptoms.

CoQ10 supplements have been consumed by millions of people for nearly 30 years without serious adverse effects. That is because CoQ10 exists naturally in the human body, and therefore there are no adverse side effects from restoring this vital nutrient to its normal level. In tests of thousands of people in Japan, Europe and the United States over a period of more than 30 years, no toxicity has ever been shown, no matter how high the intake amount.

Ubiquinol is required for the body to generate energy. Restoring this vital nutrient to optimal levels in people over 40 will restore the same type of youthful energy the body produced when it could efficiently convert CoQ10 to ubiquinol and maintain adequate concentrations of ubiquinol in plasma and tissues. Thus, supplementing with WIN CoQ10 is the ideal way to restore and sustain your natural energy.

Scientists and researchers at Kaneka Corporation have been studying this nutrient for more than a decade and have conducted numerous safety and toxicity studies on the ingredient. Additionally, as a form of CoQ10, ubiquinol will have all of the same benefits of CoQ10. However, because ubiquinol has only been commercially available since 2006, scientists have only recently begun to study the specific benefits of this reduced form of CoQ10. A number of promising studies and trials are getting underway, including one on late-stage cardiovascular disease. Results from six different studies are expected by the end of 2008.